Menopause can cause sleep disruptions due to a variety of factors. Modvigil 200 can be caused by hormone levels, lifestyle and situational tensions, as well as health issues. These are some of the reasons you might have difficulty falling asleep after the age of 45 or 40.* Declining hormone levels.* Night sweats and hot flashes.* Anxiety and depression* Other medical problems like breathing problems, thyroid problems, pain, etc.* Excessive use of caffeine, nicotine or alcohol, or the use of certain supplements.* Family and social problems like ailing parents, divorcing, job worries, financial problems, etc.* Various medicines using for different physical discomforts.